Don't bro me!
I'm talking about something very specific. I think most reasonable people would acknowledge that, while treating symptoms is not the best way, there's a fundamental human right not to be in pain. Josh Bloom points out that chronic pain patients have had their pain meds cut to below therapeutic levels without anything else effective being put in place. A law has even been passed in Florida limiting opioids after surgery that he rightly calls 'an atrocity'. Doctors are in the position of forcing treatment on patients with CBP that they don't want. See link below.
In aGvHD, doctors are also in the position of having to give to patients with grades 3 & 4 acute GvHD of the gut what's basically a placebo (RUX). According to the editorial on Reach2 I read, this was good RCT, although some of the data wasn't so good. The not so good data was that there was no difference in survival! When I read that, I honestly felt like this world was becoming openly insane.
I'm speaking from a position from knowing in depth what's going on, particularly in paediatrics. If the definition of insanity is doing the same thing over and over expecting a different result, that's what I've seen.
Don't bro me!
https://www.hrw.org/node/325275/printable/print
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