this promising bit of research would have to have advantages in terms of drug development for an unmet need, given local injection at least.
Animals that received LV-NgR1 shRNA remarkably improved the motor function.
Short-hairpin RNA (shRNA) carried by lentiviral vectors could be locally injected at the lesion site to specifically silence target genes for months efficiently, meeting the therapeutic requirements for neural dysfunctions since neural repair is slow and overcomes the problems mentioned before9
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