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IGF-1 trial observations

  1. 144 Posts.
    My apologies if this has already been covered. I was reading about past IGF-1 trials, and ran into this FB page with comments on how the patients are going on the Phase 2 IGF-1 Rett trial. It is recent with last comments from yesterday.

    Please scroll down and see all the posts and comments too. The comments on observed improvements are almost exactly the same as the social media comments we had heard from parents of the nnz-2566 trial.

    The question in my mind is, will the FDA approve the drug (nnz-2566) solely on reduced seizures, better breathing, better eye contact, normalised EEGs, and less hand wringing (assuming all of those improvements are 'proven' - which is looking more and more likely)? i.e. will the FDA approve something on symptom alleviation only, not necessarily a cure?
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