BTA 0.00% 57.0¢ biota holdings limited

hear that rumble ?

  1. 2,961 Posts.
    This morning I heard a report on the ABC of a published research document which went on in Quack speak to deatil that existing drugs used " To treat cold and Flu" by usine live virus ( RELENZA / FLUNET) could via clinical trials be simply modified to attach to the cronovirus that causes SARS.
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    NEW ENGLAND JOURNAL :-
    Published at www.nejm.org April 10, 2003 (10.1056/NEJMoa030747)


    Identification of a Novel Coronavirus in Patients with Severe Acute Respiratory Syndrome

    Christian Drosten, M.D., Stephan Günther, M.D., Wolfgang Preiser, M.D., Sylvie van der Werf, Ph.D., Hans-Reinhard Brodt, M.D., Stephan Becker, Ph.D., Holger Rabenau, Ph.D., Marcus Panning, M.D., Larissa Kolesnikova, Ph.D., Ron A.M. Fouchier, Ph.D., Annemarie Berger, Ph.D., Ana-Maria Burguière, Ph.D., Jindrich Cinatl, Ph.D., Markus Eickmann, Ph.D., Nicolas Escriou, Ph.D., Klaus Grywna, M.Sc., Stefanie Kramme, M.D., Jean-Claude Manuguerra, Ph.D., Stefanie Müller, M.Sc., Volker Rickerts, M.D., Martin Stürmer, Ph.D., Simon Vieth, Hans-Dieter Klenk, M.D., Albert D.M.E. Osterhaus, Ph.D., Herbert Schmitz, M.D., and Hans Wilhelm Doerr, M.D.


    ABSTRACT


    Background The severe acute respiratory syndrome (SARS) has recently been identified as a new clinical entity. SARS is thought to be caused by an unknown infectious agent.

    Methods Clinical specimens from patients with SARS were searched for unknown viruses with the use of cell cultures and molecular techniques.

    Results A novel coronavirus was identified in patients with SARS. The virus was isolated in cell culture, and a sequence 300 nucleotides in length was obtained by a polymerase-chain-reaction (PCR)-based random-amplification procedure. Genetic characterization indicated that the virus is only distantly related to known coronaviruses (identical in 50 to 60 percent of the nucleotide sequence). On the basis of the obtained sequence, conventional and real-time PCR assays for specific and sensitive detection of the novel virus were established. Virus was detected in a variety of clinical specimens from patients with SARS but not in controls. High concentrations of viral RNA of up to 100 million molecules per milliliter were found in sputum. Viral RNA was also detected at extremely low concentrations in plasma during the acute phase and in feces during the late convalescent phase. Infected patients showed seroconversion on the Vero cells in which the virus was isolated.

    Conclusions The novel coronavirus might have a role in causing SARS.

    If / when Biota announce a further link and or the phase 1 clinicals - their will be a massive surge to get on the register. BTA has not got a large amount of stock our their and the problems with Kahn are finished.

    That leaves no major shareholder and the beginings of some very intertetesting times.

    Watch this space....


    Singas


    - ADVICE _
    This post is for information purposes only, and does not constitute an investment recommendation. Always refer to the red disclaimer and seek investment advice.

 
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